Pathophysiology of gastroesophageal reflux disease in infants and non-pharmacologic strategies for symptom management

Gastroesophageal reflux is a common, but complex pathophysiologic process in young infants. Recent clinical practice guidelines suggest use of non-pharmacologic management strategies given concerns about the safety and effectiveness of acid-reducing medications in this population. In this paper, we holistically review the pathophysiology of gastroesophageal reflux disease with a focus on identify symptom management targets. Symptom management strategies include targeting stress, alterations in the intestinal microbiome, food intolerances, feeding difficulties, and positioning.

Authors: Britt Pados & Emma Davitt

Publication information: Nursing for Women’s Health. 2020; 24(2): 101-114. doi: 10.1016/j.nwh.2020.01.005

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